Interest of postmortem-collected specimens in the diagnosis of fulminant meningococcal sepsis

Diagn Microbiol Infect Dis. 2005 May;52(1):65-6. doi: 10.1016/j.diagmicrobio.2004.12.012.

Abstract

We reported the case of a child who died of purpura fulminans. The diagnosis of Neisseria meningitidis serogroup C could be assessed using postmortem specimens collected up to 10 h after death. We were able to identify the bacteria by culture and/or PCR on samples without having autopsy performed. Soluble antigens were also detected in serum.

Publication types

  • Case Reports

MeSH terms

  • Antigens, Bacterial / blood
  • Autopsy*
  • Culture Media
  • Fatal Outcome
  • Humans
  • IgA Vasculitis / diagnosis*
  • IgA Vasculitis / microbiology
  • Infant
  • Male
  • Meningococcal Infections / diagnosis*
  • Meningococcal Infections / microbiology
  • Neisseria meningitidis, Serogroup C / genetics
  • Neisseria meningitidis, Serogroup C / isolation & purification*
  • Polymerase Chain Reaction
  • Sepsis / diagnosis*
  • Sepsis / microbiology
  • Specimen Handling / methods

Substances

  • Antigens, Bacterial
  • Culture Media