Traditional aqueous kava extracts inhibit cytochrome P450 1A2 in humans: Protective effect against environmental carcinogens?

Clin Pharmacol Ther. 2005 May;77(5):453-4. doi: 10.1016/j.clpt.2005.01.021.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Carcinogens, Environmental / adverse effects*
  • Cytochrome P-450 CYP1A2 / drug effects
  • Cytochrome P-450 CYP1A2 / metabolism
  • Cytochrome P-450 CYP1A2 Inhibitors*
  • Female
  • Forecasting
  • Humans
  • Kava / chemistry*
  • Male
  • Medicine, East Asian Traditional*
  • New Caledonia / ethnology
  • Plant Extracts / administration & dosage
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacokinetics*
  • Self Administration
  • Time Factors
  • Up-Regulation
  • Water

Substances

  • Carcinogens, Environmental
  • Cytochrome P-450 CYP1A2 Inhibitors
  • Plant Extracts
  • Water
  • Cytochrome P-450 CYP1A2