Abstract
[reaction: see text]. A directed library of anilinogeranyl diphosphate analogues of the isoprenoid farnesyl diphosphate has been prepared by solid-phase organic synthesis using a traceless linker strategy in moderate yield in three steps: reductive amination, bromination, and treatment with ((n-Bu)4N)3HP2O7.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Acyclic Monoterpenes
-
Alcohols / chemical synthesis
-
Alcohols / chemistry
-
Aniline Compounds / chemical synthesis*
-
Aniline Compounds / chemistry
-
Combinatorial Chemistry Techniques*
-
Molecular Structure
-
Polyisoprenyl Phosphates / chemical synthesis*
-
Polyisoprenyl Phosphates / chemistry
-
Sesquiterpenes
-
Terpenes / chemical synthesis*
-
Terpenes / chemistry
Substances
-
Acyclic Monoterpenes
-
Alcohols
-
Aniline Compounds
-
Polyisoprenyl Phosphates
-
Sesquiterpenes
-
Terpenes
-
farnesyl pyrophosphate
-
geraniol