Immunology: how do T cells recognize antigen?

Curr Biol. 2005 May 24;15(10):R382-5. doi: 10.1016/j.cub.2005.05.001.

Abstract

T cells recognize small fragments of microorganisms (antigens) on the surface of other cells using T cell antigen receptors. The mechanism by which these receptors signal into T cells is controversial, but two recent studies provide important new clues.

Publication types

  • Review

MeSH terms

  • Antigens / immunology*
  • Antigens / metabolism
  • Humans
  • Immunity, Cellular / immunology*
  • Major Histocompatibility Complex / immunology
  • Models, Immunological*
  • Receptors, Antigen, T-Cell / metabolism*
  • Signal Transduction / immunology*
  • T-Lymphocytes / immunology*

Substances

  • Antigens
  • Receptors, Antigen, T-Cell