The effects of milacemide on item and source memory

Clin Neuropharmacol. 1992 Apr;15(2):114-9. doi: 10.1097/00002826-199204000-00005.

Abstract

Prior research has shown that memory for facts and items (item memory) and memory for where one has learned these items (source memory) can be dissociated under certain conditions. In this study, we examined the effects of milacemide, a derivative of glycine, on memory for item and source information in healthy young and older adults. These results pointed to a dissociation between source memory and item memory: Milacemide administration seemed to facilitate memory for source information but did not affect recognition memory.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetamides / pharmacology*
  • Adult
  • Aged
  • Aging / physiology
  • Female
  • Humans
  • Male
  • Memory / drug effects*
  • Memory / physiology
  • Middle Aged
  • Monoamine Oxidase Inhibitors / pharmacology*

Substances

  • Acetamides
  • Monoamine Oxidase Inhibitors
  • milacemide