Abstract
Two new quinic acid esters (1 and 2) were isolated from the extract of Ipomoea pes-caprae together with six known quinic acid esters (3-8). The structures of compounds 1 and 2 were elucidated by spectroscopic data interpretation. These new compounds exhibited collagenase inhibitory activity and showed almost no cytotoxicity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / isolation & purification*
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Enzyme Inhibitors / pharmacology
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Esters
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Ipomoea / chemistry*
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Matrix Metalloproteinase Inhibitors*
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Plant Leaves / chemistry
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Plants, Medicinal / chemistry*
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Quinic Acid* / analogs & derivatives*
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Quinic Acid* / chemistry
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Quinic Acid* / isolation & purification
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Quinic Acid* / pharmacology
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Thailand
Substances
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3,5-di-O-caffeoyl-4-O-coumaroylquinic acid
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4,5-di-O-caffeoyl-1,3-di-O-coumaroylquinic acid
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Enzyme Inhibitors
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Esters
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Matrix Metalloproteinase Inhibitors
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Quinic Acid