Temporal changes in bacterial resistance in German intensive care units, 2001-2003: data from the SARI (surveillance of antimicrobial use and antimicrobial resistance in intensive care units) project

J Hosp Infect. 2005 Aug;60(4):348-52. doi: 10.1016/j.jhin.2004.12.027.

Abstract

Conservative testing revealed a stable antibiotic resistance situation for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Enterobacter cloacae in 32 German intensive care units (ICUs) actively participating in the SARI (surveillance of antimicrobial use and antimicrobial resistance in ICUs) project over a three-year period (2001--2003). No significant changes were shown for methicillin-resistant S. aureus (MRSA) (P=0.501; the MRSA rate increased in 18 ICUs and decreased in 14 ICUs). The only exception was an increase in ciprofloxacin-resistant E. coli.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacteria / drug effects*
  • Bacteria / isolation & purification
  • Bacterial Infections / drug therapy
  • Bacterial Infections / microbiology*
  • Ciprofloxacin / pharmacology
  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • Drug Resistance, Bacterial*
  • Enterobacter cloacae / drug effects*
  • Enterobacter cloacae / isolation & purification
  • Escherichia coli / drug effects*
  • Escherichia coli / isolation & purification
  • Germany
  • Humans
  • Intensive Care Units / statistics & numerical data*
  • Klebsiella pneumoniae / drug effects*
  • Klebsiella pneumoniae / isolation & purification
  • Methicillin Resistance
  • Microbial Sensitivity Tests
  • Pseudomonas aeruginosa / drug effects*
  • Pseudomonas aeruginosa / isolation & purification
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin