[Parkinson's disease, progressive lumbar kyphosis and focal paraspinal myositis]

Rev Neurol (Paris). 2005 Apr;161(4):459-63. doi: 10.1016/s0035-3787(05)85077-5.
[Article in French]

Abstract

Introduction: The camptocormia (bent spine) is characterized by a severe forward flexion of the thoracolumbar spine which disappears in the supine position. Clinical case. We describe a typical case observed in a parkinsonian patient. The MRI, electromyogram and biopsy of the paraspinal muscles revealed a typical myositis pattern.

Discussion: This case, the sixth published to our knowledge, confirms that focal myositis is associated with the camptocormia in Parkinson's disease. Typically it is observed in male subjects, appearing 4 to 6 years after the onset of Parkinson's disease, in fluctuating patients treated by an association of L-Dopa and agonist. It appears quickly and becomes the most important symptom. Antiparkinsonian drugs are useless.

Conclusion: This exceptional picture raises original pathophysiological and therapeutic questions. Systematic studies should be performed in order to detail the pathophysiological link between these 3 entities: Parkinson's disease, focal myositis and camptocormia.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Disease Progression
  • Humans
  • Kyphosis / complications*
  • Lumbar Vertebrae
  • Male
  • Middle Aged
  • Myositis / complications*
  • Parkinson Disease / complications*