[Repeated administration of t-PA and abciximab in a patient with anterior myocardial infarction--a case report]

Kardiol Pol. 2005 May;62(5):462-6; discussion 466.
[Article in Polish]

Abstract

Repeated administration of t-PA and abciximab in a patient with anterior myocardial infarction - a case report. A case of a 40-year-old male with acute anterior myocardial infarction (MI) is presented. Due to the angiographic equipment failure, the patient did not undergo primary angioplasty and received heparin and 100 mg of t-PA. This treatment was associated with clinical and ECG signs of reperfusion, however, 30 minutes after completion of t-PA infusion, the patient developed clinical and ECG signs of re-occlusion. The decision was made to transfer the patient to a catheterisation laboratory for further invasive treatment, however, it was located 200 km from our centre. Because of that, the patient received another dose of 50 mg of t-PA and abciximab before transportation. Further course was uncomplicated and the patient underwent successful stent implantation in the other centre.

Publication types

  • Case Reports

MeSH terms

  • Abciximab
  • Adult
  • Antibodies, Monoclonal / administration & dosage*
  • Coronary Angiography
  • Electrocardiography
  • Fibrinolytic Agents / administration & dosage
  • Humans
  • Immunoglobulin Fab Fragments / administration & dosage*
  • Male
  • Myocardial Infarction / drug therapy*
  • Myocardial Infarction / physiopathology
  • Platelet Aggregation Inhibitors / administration & dosage
  • Thrombolytic Therapy / methods*
  • Tissue Plasminogen Activator / administration & dosage*
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal
  • Fibrinolytic Agents
  • Immunoglobulin Fab Fragments
  • Platelet Aggregation Inhibitors
  • Tissue Plasminogen Activator
  • Abciximab