Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata

Chem Pharm Bull (Tokyo). 2005 Jun;53(6):694-5. doi: 10.1248/cpb.53.694.

Abstract

Two known retrochalcones, licochalcone A (1) and licochalcone C (2), and one new retrochalcone, licochalcone E (4) were isolated by cytotoxicity-guided fractionation from the roots of Glycyrrhiza inflata along with an ordinary chalcone, isoliquiritigenin (3). The structure of the new retrochalcone was elucidated through a spectroscopic analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Chalcones / chemistry
  • Chalcones / isolation & purification
  • Chalcones / toxicity*
  • Cytotoxins / chemistry
  • Cytotoxins / isolation & purification
  • Cytotoxins / toxicity*
  • Glycyrrhiza / toxicity*
  • Humans
  • Plant Roots*

Substances

  • Chalcones
  • Cytotoxins