Abstract
There has been minimal clinical experience with the use of the Aspergillus galactomannan enzyme-linked immunosorbent assay (ELISA) for patients receiving echinocandin therapy. We reviewed the experience with the galactomannan ELISA for 17 patients in a study of caspofungin treatment for invasive aspergillosis. The rate of successful outcomes for these patients was similar to that overall for participants in the study. Trends in antigenemia levels correlated with clinical and radiographic findings.
Publication types
-
Evaluation Study
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adult
-
Aged
-
Antifungal Agents / therapeutic use*
-
Antigens, Fungal / blood*
-
Aspergillosis / drug therapy*
-
Aspergillosis / microbiology
-
Caspofungin
-
Echinocandins
-
Enzyme-Linked Immunosorbent Assay
-
Female
-
Galactose / analogs & derivatives
-
Humans
-
Lipopeptides
-
Lung Diseases, Fungal / drug therapy*
-
Lung Diseases, Fungal / microbiology
-
Mannans / blood*
-
Middle Aged
-
Peptides, Cyclic / therapeutic use*
-
Treatment Outcome
Substances
-
Antifungal Agents
-
Antigens, Fungal
-
Echinocandins
-
Lipopeptides
-
Mannans
-
Peptides, Cyclic
-
galactomannan
-
Caspofungin
-
Galactose