Steroid-induced avascular necrosis of the hip in neurosurgical patients: epidemiological study

ANZ J Surg. 2005 Jun;75(6):409-10. doi: 10.1111/j.1445-2197.2005.03389.x.

Abstract

Background: Avascular necrosis (AVN) of the femoral head is perceived to be a rare complication of short-term steroid therapy for neurosurgical conditions but its precise risk is unknown.

Methods: Retrospective review of hospital records between 1994 and 2001.

Results: The risk of developing AVN of the femoral head is 0.3% with an incidence of one per one thousand patients per year.

Conclusions: It would be advisable to minimize both the dosage and the duration of steroid treatment where possible.

MeSH terms

  • Adult
  • Dexamethasone / administration & dosage
  • Dexamethasone / adverse effects
  • Female
  • Femur Head Necrosis / chemically induced*
  • Femur Head Necrosis / epidemiology*
  • Humans
  • Male
  • Neurosurgical Procedures*
  • Postoperative Complications
  • Retrospective Studies
  • Steroids / administration & dosage
  • Steroids / adverse effects*

Substances

  • Steroids
  • Dexamethasone