Recombination at collapsed replication forks: the payoff for survival

Mol Cell. 2005 Jun 10;18(6):614-5. doi: 10.1016/j.molcel.2005.05.018.

Abstract

Recombination is believed to assist replication when forks collapse. By using an elegant system, Lambert et al. (2005) address the consequences of recombination at blocked forks. They show that chromosomal rearrangements are the price to pay for cell viability when forks collapse.

Publication types

  • Comment

MeSH terms

  • DNA Replication*
  • DNA, Single-Stranded
  • Escherichia coli
  • Gene Rearrangement
  • Recombination, Genetic*
  • Schizosaccharomyces

Substances

  • DNA, Single-Stranded