Adhesion formation and interanimal variability in a laparoscopic mouse model varies with strains

Fertil Steril. 2005 Jun;83(6):1871-4. doi: 10.1016/j.fertnstert.2004.11.084.

Abstract

Adhesion formation after laparoscopic surgery was evaluated in mice of different strains. More adhesions were observed in Swiss, NMRI, and BALB/c mice, with less interanimal variability in BALB/c mice. These data point to genetics effects on adhesion formation, which open new insights in its pathogenesis and indicate the importance of a careful strain selection for animal studies.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Disease Models, Animal
  • Female
  • Laparoscopy / adverse effects*
  • Laparoscopy / statistics & numerical data
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Models, Animal
  • Postoperative Complications
  • Species Specificity
  • Tissue Adhesions / genetics*
  • Tissue Adhesions / physiopathology