Selective laser trabeculoplasty (SLT) complicated by intraocular pressure elevation in eyes with heavily pigmented trabecular meshworks

Am J Ophthalmol. 2005 Jun;139(6):1110-3. doi: 10.1016/j.ajo.2004.11.038.

Abstract

Purpose: To report and assess the complication of intraocular pressure (IOP) elevations after selective laser trabeculoplasty (SLT) in patients with heavily pigmented trabecular meshworks.

Design: Noncomparative, observational case series.

Methods: Retrospective analysis of the medical files of four glaucoma patients with heavily pigmented trabecular meshwork, who presented with IOP elevations after SLT.

Results: All four glaucoma patients presented with post-SLT IOP elevations. Three had features of pigmentary dispersion syndrome, and the fourth had a heavily pigmented trabecular meshwork. Two patients had previous argon laser trabeculoplasty (ALT) in the same eye in which SLT was performed, and one had a previous ocular trauma. Eventually, three of the patients required surgical trabeculectomy.

Conclusions: This case series suggests that post-SLT IOP elevations can be a serious adverse event in some glaucomatous patients. It is recommended by the authors that patients with a deeply pigmented trabecular meshwork, taking multiple topical medications and having previous ALT treatment, should be considered at higher risk for this complication.

MeSH terms

  • Adult
  • Exfoliation Syndrome / surgery
  • Female
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Hyperpigmentation / surgery*
  • Intraocular Pressure*
  • Laser Therapy / methods*
  • Male
  • Middle Aged
  • Ocular Hypertension / etiology*
  • Retrospective Studies
  • Trabecular Meshwork / pathology
  • Trabecular Meshwork / surgery*
  • Trabeculectomy / adverse effects*