Lewis acid-catalyzed stereospecific ring expansion of aziridine-2-carboxylates to imidazolidin-2-ones

Chem Commun (Camb). 2005 Jun 28:(24):3062-4. doi: 10.1039/b503750f. Epub 2005 May 9.

Abstract

Lewis acid-catalyzed ring expansion reaction of chiral aziridine-2-carboxylate proceeds regio- and stereospecifically to yield enantiomerically pure 4-functionalized imidazolidin-2-ones in high yields.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aziridines / chemistry*
  • Carboxylic Acids / chemistry*
  • Catalysis
  • Imidazolidines / chemical synthesis*
  • Stereoisomerism

Substances

  • Aziridines
  • Carboxylic Acids
  • Imidazolidines