Abstract
We found a 13% macrolide resistance in 3,866 Streptococcus pyogenes isolated from tonsillopharyngitis patients; 59% macrolide-resistant isolates were distributed in 5 clones, suggesting the importance of both resistance gene transfer and clonal dissemination in the spread of these organisms. We also report one of the largest collections of telithromycin-resistant isolates.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / pharmacology*
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Child
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Child, Preschool
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Drug Resistance, Bacterial* / genetics
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Humans
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Infant
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Ketolides / pharmacology*
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Macrolides / pharmacology*
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Microbial Sensitivity Tests
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Middle Aged
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Population Surveillance
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Streptococcal Infections / epidemiology*
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Streptococcal Infections / microbiology
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Streptococcus pyogenes / classification
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Streptococcus pyogenes / drug effects*
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Streptococcus pyogenes / genetics
Substances
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Anti-Bacterial Agents
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Ketolides
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Macrolides
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telithromycin