Abstract
After increasing from 1995 to 1999, invasive erythromycin-nonsusceptible Streptococcus pneumoniae rates per 100,000 decreased 53.6% in children from Baltimore, Maryland (US), from 1999 to 2001, which was partially attributed to strains related to the mefE-carrying England14-9 clone. The decline in infection rates was likely due to the pneumococcal 7-valent conjugate vaccine.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Anti-Bacterial Agents / pharmacology*
-
Bacterial Proteins / genetics
-
Child
-
Child, Preschool
-
Drug Resistance, Bacterial* / genetics
-
Erythromycin / pharmacology*
-
Humans
-
Incidence
-
Infant
-
Infant, Newborn
-
Maryland / epidemiology
-
Membrane Proteins / genetics
-
Microbial Sensitivity Tests
-
Pneumococcal Infections / epidemiology*
-
Pneumococcal Infections / microbiology
-
Streptococcus pneumoniae / drug effects*
Substances
-
Anti-Bacterial Agents
-
Bacterial Proteins
-
MefE protein, Streptococcus pneumoniae
-
Membrane Proteins
-
Erythromycin