Acute demyelinating encephalomyelitis (ADEM), cryptococcal reactivation and disseminated Herpes simplex in an HIV infected child following HAART

Ronald van Toorn; Fiona Kritzinger; Helena Rabie

doi:10.1016/j.ejpn.2005.02.002

Acute demyelinating encephalomyelitis (ADEM), cryptococcal reactivation and disseminated Herpes simplex in an HIV infected child following HAART

Eur J Paediatr Neurol. 2005;9(5):355-9. doi: 10.1016/j.ejpn.2005.02.002. Epub 2005 Jun 23.

Authors

Ronald van Toorn¹, Fiona Kritzinger, Helena Rabie

Affiliation

¹ Department of Pediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University and Tygerberg Children's Hospital, P.O. Box 19063, Tygerberg 7505, South Africa. [email protected]

PMID: 15979358
DOI: 10.1016/j.ejpn.2005.02.002

Abstract

Highly active antiretroviral treatment (HAART) is increasingly becoming available for HIV infected children in South Africa. We describe a 7-year-old HIV infected child (CD4=10, viral load =180,669copies/ml) who develops a cryptococcal meningitis, with raised intracranial pressure, complicated by ADEM and disseminated Herpes simplex infection following commencement of HAART.

Publication types

Case Reports

MeSH terms

Acute Disease
Antiretroviral Therapy, Highly Active / adverse effects*
Child
Cryptococcus / drug effects
Cryptococcus / physiology
Demyelinating Diseases / chemically induced*
Demyelinating Diseases / diagnosis
Encephalomyelitis / chemically induced*
Encephalomyelitis / diagnosis
HIV Infections / drug therapy*
HIV Infections / virology
Herpes Simplex / chemically induced*
Humans
Intracranial Pressure
Magnetic Resonance Imaging
Male
Meningitis, Cryptococcal / chemically induced*
Meningitis, Cryptococcal / physiopathology
Viral Load
Virus Activation