Effect of intracoronary aqueous oxygen on left ventricular remodeling after anterior wall ST-elevation acute myocardial infarction

Hazem M Warda; Jeroen J Bax; Johan G Bosch; Douwe E Atsma; J Wouter Jukema; Ernst E van der Wall; Arnoud van der Laarse; Martin J Schalij; Pranobe V Oemrawsingh

doi:10.1016/j.amjcard.2005.02.037

Effect of intracoronary aqueous oxygen on left ventricular remodeling after anterior wall ST-elevation acute myocardial infarction

Am J Cardiol. 2005 Jul 1;96(1):22-4. doi: 10.1016/j.amjcard.2005.02.037.

Authors

Hazem M Warda¹, Jeroen J Bax, Johan G Bosch, Douwe E Atsma, J Wouter Jukema, Ernst E van der Wall, Arnoud van der Laarse, Martin J Schalij, Pranobe V Oemrawsingh

Affiliation

¹ Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.

PMID: 15979426
DOI: 10.1016/j.amjcard.2005.02.037

Abstract

The present report describes outcomes of randomized selective intracoronary aqueous oxygen versus standard care in patients who had acute anterior wall myocardial infarction within 6 hours of onset (n = 50). Left ventricular (LV) dimensions and function were assessed by contrast echocardiography at baseline and 1 month. It is demonstrated that aqueous oxygen prevents LV remodeling and preserves LV ejection fraction.

Publication types

Clinical Trial
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Contrast Media / administration & dosage
Echocardiography
Female
Humans
Male
Middle Aged
Myocardial Infarction / complications*
Oxygen / administration & dosage
Oxygen / chemistry
Oxygen / therapeutic use*
Solubility
Stroke Volume
Treatment Outcome
Ventricular Remodeling*
Water / chemistry

Substances

Contrast Media
Water
Oxygen