The patterns of care study for breast-conserving therapy in Japan: analysis of process survey from 1995 to 1997

Int J Radiat Oncol Biol Phys. 2005 Jul 15;62(4):1048-54. doi: 10.1016/j.ijrobp.2004.12.055.

Abstract

Purpose: To present the results of a process survey on breast-conserving therapy (BCT) in Japan from 1995 to 1997.

Methods and materials: From September 1998 to December 1999, data on the treatment process of 865 randomly selected BCT patients were collected by extramural audits.

Results: For primary surgery, wide excision or tumorectomy was performed in 372 patients (43.0%), and quadrantectomy or segmental mastectomy was performed in 493 patients (57%). The extent of axillary dissection was equal or beyond Level II in 590 patients (68.2%). Systemic chemotherapy was administered to 103 of 160 node-positive patients (64.4%) and 180 of 569 node-negative patients (31.6%). Tamoxifen was administered to 234 of 323 hormone receptor-positive patients (72.5%) and 68 of 130 hormone receptor-negative patients (52.3%). Photon energy of 10 MV was administered for whole breast irradiation in 38 patients (4.4%) without bolus.

Conclusions: The extent of surgical resection for BCT was large in Japan. Pathologic assessment and the technique of radiation therapy were apparently suboptimal in some cases. Information on prognostic/predictive factors was not fully utilized to individualize systemic adjuvant therapy. Establishment and widespread use of guidelines for BCT for in Japan are desirable. Repeated surveys will demonstrate how such guidelines affect clinical practices.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery*
  • Chemotherapy, Adjuvant
  • Female
  • Humans
  • Japan
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Mastectomy, Segmental*
  • Middle Aged
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians'*
  • Tamoxifen / therapeutic use

Substances

  • Antineoplastic Agents, Hormonal
  • Tamoxifen