Ruthenium-catalysed asymmetric hydrogenation of ketones using QUINAPHOS as the ligand

Chem Commun (Camb). 2005 Jul 21:(27):3460-2. doi: 10.1039/b505195a. Epub 2005 Jun 9.

Abstract

Highly enantioselective ruthenium-catalysed hydrogenation of aromatic ketones is achieved with (Ra,S(C))-QUINAPHOS in the presence of achiral and chiral diamines as co-catalysts.