Abstract
Four cases of infection by extended spectrum beta-lactamase-producing Klebsiella pneumoniae occurred in the neonatal intensive care unit. Isolation, empiric therapy change and education produced no effect. Newborn weekly colonization rates were 0-18.7%. One health care worker with onychomycosis was positive for extended spectrum beta-lactamase-producing K. pneumoniae. Isolates were identical by molecular typing. Outbreak was controlled when the health care worker was excluded from the neonatal intensive care unit.
MeSH terms
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Adult
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Aminoglycosides / pharmacology
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Anti-Bacterial Agents / pharmacology
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Cephalosporins / pharmacology
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Cross Infection / epidemiology
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Cross Infection / microbiology
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Disease Outbreaks*
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Drug Resistance, Bacterial
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Hand / microbiology
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Hand Dermatoses / complications
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Hand Dermatoses / microbiology
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Health Personnel
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Humans
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Infant, Newborn
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Intensive Care Units, Neonatal*
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Klebsiella Infections / epidemiology*
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Klebsiella pneumoniae / drug effects
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / isolation & purification
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Onychomycosis / complications
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beta-Lactamases / metabolism*
Substances
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Aminoglycosides
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Anti-Bacterial Agents
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Cephalosporins
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beta-Lactamases