The broadening use of imaging management systems in radiology and other disciplines is due in large part to the success of the DICOM standard (Digital Imaging and Communications in Medicine), which has been accepted worldwide for more than 10 years and meanwhile represents one of the most successful standards in medicine. The central intent of establishing the initiative "Integrating the Healthcare Enterprise" (IHE) was to ensure interoperability of different IT systems in medical processes. IHE is essentially based on widespread standards such as DICOM or HL7. This overview article briefly addresses the principles and organization of DICOM and IHE and describes the current developments in both domains.