Get a grip: integrins in cell-biomaterial interactions

Biomaterials. 2005 Dec;26(36):7525-9. doi: 10.1016/j.biomaterials.2005.05.029.

Abstract

Integrin adhesion receptors have emerged as central regulators of cell-biomaterial interactions. This opinion paper discusses how integrins control cellular and host responses to biomaterials and new strategies to manipulate these adhesive interactions in order to elicit specific cellular responses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adsorption
  • Animals
  • Biocompatible Materials / chemistry*
  • Cell Adhesion
  • Humans
  • Inflammation
  • Integrins / metabolism*
  • Models, Biological
  • Oligopeptides / chemistry
  • RNA Interference
  • Signal Transduction
  • Surface Properties

Substances

  • Biocompatible Materials
  • Integrins
  • Oligopeptides
  • arginyl-glycyl-aspartic acid