GATA1 mutation analysis demonstrates two distinct primary leukemias in a child with down syndrome; implications for leukemogenesis

J Pediatr Hematol Oncol. 2005 Jul;27(7):408-9. doi: 10.1097/01.mph.0000172223.04694.c4.
No abstract available

Publication types

  • Letter

MeSH terms

  • Bone Marrow Cells / pathology
  • DNA Mutational Analysis
  • DNA-Binding Proteins / genetics*
  • Down Syndrome / genetics*
  • Erythroid-Specific DNA-Binding Factors
  • Female
  • GATA1 Transcription Factor
  • Humans
  • Leukemia, Myeloid, Acute / genetics
  • Mutation*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • Transcription Factors / genetics*

Substances

  • DNA-Binding Proteins
  • Erythroid-Specific DNA-Binding Factors
  • GATA1 Transcription Factor
  • GATA1 protein, human
  • Transcription Factors