Cortical development: the art of generating cell diversity

Development. 2005 Aug;132(15):3327-32. doi: 10.1242/dev.01931.

Abstract

The fascinating question of how the enormous diversity of neuronal and glial cells in the cerebral cortex is generated during development was recently discussed at a meeting on cortical development and stem cells in Greece. What emerged from this meeting is an equally fascinating answer, namely that precursor diversity at rather early stages of development anticipates later cell type diversity.

Publication types

  • Review

MeSH terms

  • Animals
  • Cerebral Cortex / embryology
  • Cerebral Cortex / growth & development*
  • Cilia / physiology
  • Genetic Variation*
  • Humans
  • Mice
  • Microvilli / physiology
  • Morphogenesis
  • Neuroglia / cytology
  • Neuroglia / physiology
  • Neurons / cytology
  • Neurons / physiology