Abstract
Using clinical samples from patients with severe acute respiratory syndrome, we showed that the sensitivities of a quantitative reverse transcription-polymerase chain reaction (80% for fecal samples and 25% for urine samples) were higher than those of the polyclonal (50% and 5%) and monoclonal (35% and 8%) antibody-based nucleocapsid antigen capture enzyme-linked immunosorbent assays.
Publication types
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Comparative Study
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Enzyme-Linked Immunosorbent Assay* / methods
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Feces / virology
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Humans
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Nucleocapsid Proteins / isolation & purification
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Reverse Transcriptase Polymerase Chain Reaction / methods
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Sensitivity and Specificity
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Severe Acute Respiratory Syndrome / diagnosis*
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Severe Acute Respiratory Syndrome / urine
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Severe acute respiratory syndrome-related coronavirus / isolation & purification*