Synthesis and biological evaluation of lipophilic iron chelators as protective agents from oxidative stress

Org Biomol Chem. 2005 Aug 7;3(15):2685-7. doi: 10.1039/b507385p. Epub 2005 Jul 1.

Abstract

Lipophilic Fe(III) chelators were synthesized and shown to protect oligodendrial cells from oxidative damage induced by Fe(III) and hydrogen peroxide.

MeSH terms

  • Iron Chelating Agents / chemical synthesis*
  • Iron Chelating Agents / chemistry
  • Iron Chelating Agents / pharmacology*
  • Lipids / chemistry*
  • Oxidative Stress / drug effects*

Substances

  • Iron Chelating Agents
  • Lipids