Lung function in patients operated for chronic pleural empyema

Thorac Cardiovasc Surg. 2005 Aug;53(4):245-9. doi: 10.1055/s-2005-837646.

Abstract

Objectives: To evaluate lung function after lung decortication in patients operated for chronic pleural empyema.

Methods and materials: To determine the lung function after lung decortication in 20 men (71.4%) and 8 women (28.6%) a prospective evaluation of blood gases, spirometry, lung perfusion, ventilation, and alveolar permeability were performed 28 weeks (15-60 weeks) after the operation.

Results: Median lung perfusion on the affected side was 45.2% (26.1-55.3%) in 13 right and 36% (13.8-47.2%) in 15 left empyemas, and was within normal limits in 4/28 cases. The mean lung ventilation was 44.4% (21.5-54%) and 37% (18.9-50.6%) in patients affected on the right or left side, respectively. Ventilation perfusion inequality occurred in 22 patients (78.6%). Dynamic ventilation scintigraphy revealed impairment of epithelial integrity in 10 cases (35.7%). Individual analysis revealed that 15 patients (53.6%) showed a severe reduction in one of the examinations and 8 (28.6%) in more than one.

Conclusions: Although the separate analysis of the different functional parameters revealed a mild reduction of lung function after decortication, in the majority of patients the impairment was more severe due to multilevel functional lung damage.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Blood Gas Analysis
  • Chi-Square Distribution
  • Chronic Disease
  • Electrocardiography
  • Empyema, Pleural / diagnosis*
  • Empyema, Pleural / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Lung Volume Measurements
  • Male
  • Middle Aged
  • Pneumonectomy / methods*
  • Postoperative Period
  • Probability
  • Prospective Studies
  • Pulmonary Gas Exchange
  • Respiratory Function Tests*
  • Risk Assessment
  • Severity of Illness Index
  • Spirometry
  • Statistics, Nonparametric
  • Treatment Outcome