Abstract
Two strains of Enterobacteriaceae, Escherichia coli and Klebsiella pneumoniae, producing VIM-1 were isolated for the first time in Spain. In both strains, bla(VIM-1) was found to be carried on a gene cassette inserted into a class 1 integron. The bla(VIM-1)-containing integron was located on a transferable plasmid.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Carbapenems / metabolism*
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Carbapenems / pharmacology
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Conjugation, Genetic
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Enterobacteriaceae Infections / microbiology
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Escherichia coli / drug effects
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Escherichia coli / enzymology*
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Escherichia coli / genetics
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Escherichia coli / isolation & purification
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Humans
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Integrons / genetics
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Klebsiella pneumoniae / drug effects
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / genetics
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Klebsiella pneumoniae / isolation & purification
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Plasmids / genetics
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Sequence Analysis, DNA
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Spain
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beta-Lactam Resistance
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beta-Lactamases / genetics
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beta-Lactamases / metabolism
Substances
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Anti-Bacterial Agents
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Carbapenems
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VIM-1 metallo-beta-lactamase
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beta-Lactamases
Associated data
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GENBANK/AY970968
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GENBANK/AY987853