Abstract
Carbapenemases are rare in the United States. This is the first report of a United States nosocomial outbreak of pan-resistant Pseudomonas aeruginosa infections due to an integron-borne metallo-beta-lactamase, VIM-2. This emergence of carbapenemases on mobile genetic elements in the United States warrants surveillance.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Anti-Bacterial Agents / pharmacology
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Cross Infection / epidemiology*
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Cross Infection / microbiology
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Disease Outbreaks*
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Humans
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Integrons*
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Male
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Pseudomonas Infections / epidemiology
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Pseudomonas Infections / microbiology
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Pseudomonas aeruginosa / drug effects
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Pseudomonas aeruginosa / enzymology*
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Pseudomonas aeruginosa / genetics
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Sequence Analysis, DNA
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United States / epidemiology
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beta-Lactam Resistance*
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beta-Lactamases / biosynthesis*
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beta-Lactamases / genetics
Substances
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Anti-Bacterial Agents
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beta-lactamase bla(vim-2)
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beta-Lactamases