Lack of response to systemic corticosteroids in patients with lymphangioma

Ophthalmic Plast Reconstr Surg. 2005 Jul;21(4):302-5. doi: 10.1097/01.iop.0000172179.15781.31.

Abstract

Lymphangioma is a benign nonencapsulated orbital tumor that is difficult to treat. Recently, systemic corticosteroids were advocated as a safe and effective alternative to surgical drainage of the cysts. We describe our experience with 3 cases in which proptosis progressed or did not improve despite the exclusive use of systemic steroids for 1 week, necessitating urgent surgical intervention. These three cases demonstrate that at least in some cases, steroids alone may be ineffective, and alternative interventions must be undertaken.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Glucocorticoids / therapeutic use*
  • Humans
  • Lymphangioma / diagnostic imaging
  • Lymphangioma / drug therapy*
  • Lymphangioma / pathology
  • Orbital Neoplasms / diagnostic imaging
  • Orbital Neoplasms / drug therapy*
  • Orbital Neoplasms / pathology
  • Prednisolone / therapeutic use*
  • Tomography, X-Ray Computed

Substances

  • Glucocorticoids
  • Prednisolone