Abstract
Budding yeast divide asymmetrically and must therefore align the position of the mitotic spindle with the plane of division. The success of this process is monitored by a checkpoint-signaling mechanism. Two recent papers in Molecular Cell reveal an important new facet of this signal transduction pathway.
MeSH terms
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Cell Cycle Proteins / metabolism
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Cytokinesis / physiology*
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Cytoskeletal Proteins / metabolism
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Guanine Nucleotide Exchange Factors / metabolism
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Monomeric GTP-Binding Proteins / metabolism
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Protein Kinases / metabolism
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Protein Serine-Threonine Kinases
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Saccharomyces cerevisiae / physiology*
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Saccharomyces cerevisiae Proteins / metabolism
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Signal Transduction / physiology*
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Spindle Apparatus / physiology*
Substances
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BFA1 protein, S cerevisiae
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BUB2 protein, S cerevisiae
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Cell Cycle Proteins
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Cytoskeletal Proteins
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Guanine Nucleotide Exchange Factors
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LTE1 protein, S cerevisiae
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Saccharomyces cerevisiae Proteins
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TEM1 protein, S cerevisiae
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Protein Kinases
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KIN4 kinase, S cerevisiae
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Protein Serine-Threonine Kinases
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Monomeric GTP-Binding Proteins