The Western Australian gestational breast cancer project: a population-based study of the incidence, management and outcomes

Breast. 2005 Aug;14(4):276-82. doi: 10.1016/j.breast.2005.02.008. Epub 2005 Apr 18.

Abstract

This descriptive population-based study estimates the incidence, and describes the management and outcomes for women diagnosed with gestational breast cancer (GBC) aged 15-44 years in Western Australia between January 1982 and December 2000. Gestational breast cancer accounted for 6.25% of breast cancers in Western Australian women less than 45 years of age, and complicated 23.6 per 100,000 pregnancies. Two thirds were diagnosed postpartum and a third while pregnant. The median time from first symptom to diagnosis was less than four weeks. Women diagnosed during pregnancy were more likely to have a pregnancy termination. Over 50% of women were lymph node positive and those diagnosed postpartum were more likely to have a mastectomy. Five-year survival was better than reported previously (73%). The incidence of GBC was lower than previously reported. Significant differences in pregnancy outcome and management exist between the pregnant and postpartum groups.

MeSH terms

  • Adolescent
  • Adult
  • Breast Neoplasms / epidemiology*
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / therapy
  • Female
  • Humans
  • Incidence
  • Mastectomy
  • Pregnancy
  • Pregnancy Complications, Neoplastic / epidemiology*
  • Pregnancy Complications, Neoplastic / pathology*
  • Pregnancy Complications, Neoplastic / therapy
  • Treatment Outcome
  • Western Australia / epidemiology