The role of routine culture for tuberculosis during bronchoscopy examination of lung masses

Respiration. 2005 Jul-Aug;72(4):402-5. doi: 10.1159/000086255.

Abstract

Background: Many centers routinely culture bronchoscopy samples for mycobacteria even when tuberculosis (TB) is not strongly suspected. The value of this practice has hardly been investigated.

Objective: The aim of this retrospective study was to assess the utility of routine culture of bronchoscopy samples of lung masses for mycobacteria in a region where TB is not endemic.

Patients and methods: The study group consisted of 168 patients who underwent bronchoscopy for investigation of lung masses in a major tertiary-care, university-affiliated facility in central Israel. The findings on acid-fast bacillus staining and culture were reviewed, and data on demographic characteristics were collected from the files.

Results: There were 97 men (58%) and 71 women with a mean age of 62 +/- 25 years. One culture (0.6%) grew Mycobacterium tuberculosis. There were no cases of positive acid-fast bacillus smear or positive nontuberculous mycobacteria culture. Sixty USD (5.45%) would be saved per patient without clinical suspicion of TB.

Conclusions: These findings highlight the need to formulate new guidelines for the performance of mycobacterial cultures of bronchoscopy specimens in areas with a low prevalence of TB.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Algorithms
  • Bacteriological Techniques / statistics & numerical data*
  • Bronchoscopy*
  • Comorbidity
  • Female
  • Humans
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / epidemiology*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / epidemiology*