Abstract
The main goal of this article is the development of a novel approach to construct multifunctional composite scaffolds for bone tissue engineering. For this purpose, different kinds of mineral macroporous supports, water-soluble aldehyde-containing copolymers of N-vinylpyrrolidone, as well as different nonspecific and biospecific ligands governing cell adhesion and growth have been used. The composite materials were tested initially for cytotoxicity in cell culture experiments using a model cell line.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adsorption
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Bone Substitutes / chemistry*
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Bone Substitutes / metabolism
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Bone and Bones* / cytology
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Bone and Bones* / physiology
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Cell Line
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Coated Materials, Biocompatible / chemistry*
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Coated Materials, Biocompatible / metabolism
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Humans
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Lysine / chemistry
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Minerals / chemistry*
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Molecular Structure
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Polymers / chemistry*
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Pyrrolidinones / chemistry
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Pyrrolidinones / metabolism
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Tissue Engineering / methods*
Substances
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Bone Substitutes
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Coated Materials, Biocompatible
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Minerals
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Polymers
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Pyrrolidinones
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N-vinyl-2-pyrrolidinone
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Lysine