Pulmonary arteriovenous malformation (AVM) is a rare entity with well-described signs, symptoms, and complications. Pulmonary AVMs can be congenital or acquired. They have been described in the setting of severe liver disease and after palliation with a Glenn shunt in which the hepatic venous blood flow has been excluded from the pulmonary blood flow. A variety of surgical and transcatheter interventions have been used to occlude AVMs. We report the use of the Amplatzer vascular plug to successfully occlude a pulmonary AVM in a 12-year-old patient.