Transcriptional regulation at the chromatin level in the cardiovasculature through protein-protein interactions and chemical modifications

Toru Suzuki; Takayoshi Matsumura; Ryozo Nagai

doi:10.1016/j.tcm.2005.04.003

Transcriptional regulation at the chromatin level in the cardiovasculature through protein-protein interactions and chemical modifications

Trends Cardiovasc Med. 2005 May;15(4):125-9. doi: 10.1016/j.tcm.2005.04.003.

Authors

Toru Suzuki¹, Takayoshi Matsumura, Ryozo Nagai

Affiliation

¹ Department of Cardiovascular Medicine, Graduate School of medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. [email protected]

PMID: 16099375
DOI: 10.1016/j.tcm.2005.04.003

Abstract

Transcriptional regulation in eukaryotes requires an understanding of the regulation of the chromatin structure. Chromatin is the eukaryotic-specific packaging/compaction of DNA with nucleosomal histones. This present review discusses recent advancements made in the field of chromatin-associated transcriptional regulation and their implications to the cardiovasculature.

Publication types

Review

MeSH terms

Cardiovascular Physiological Phenomena*
Chromatin / physiology*
Humans
Proteins / chemistry*
Proteins / metabolism*
Transcription, Genetic / physiology*

Substances

Chromatin
Proteins