Identification of a novel human DRB1*13 allele by sequence-based DRB typing

L Caggiari; M P Simula; A Marzotto; A Caragnano; M Luchetti; A Gabrielli; V De Re

doi:10.1111/j.1399-0039.2005.00451.x

Identification of a novel human DRB1*13 allele by sequence-based DRB typing

Tissue Antigens. 2005 Sep;66(3):246-7. doi: 10.1111/j.1399-0039.2005.00451.x.

Authors

L Caggiari¹, M P Simula, A Marzotto, A Caragnano, M Luchetti, A Gabrielli, V De Re

Affiliation

¹ Division of Experimental Oncology I, IRCCS, Centro di Riferimento Oncologico, Aviano (PN), Italy.

PMID: 16101838
DOI: 10.1111/j.1399-0039.2005.00451.x

Abstract

Herein, we report on a novel DRB1 allele (DRB1*1368) identified during sequence-based HLA-DRB typing. This new DRB1 allele is identical to DRB1*1301 at exon 2 except for a single-nucleotide substitution at codon 37, changing the amino acid Asn to Asp.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles*
Base Sequence
Exons
Female
HLA-DR Antigens / genetics*
HLA-DRB1 Chains
Histocompatibility Testing
Humans
Molecular Sequence Data
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

Substances

HLA-DR Antigens
HLA-DRB1 Chains
HLA-DRB1*13 antigen

Associated data

GENBANK/AY963587