Newer antidepressants and other nonhormonal agents for the treatment of hot flashes

Compr Ther. 2005 Fall;31(3):224-36. doi: 10.1385/comp:31:3:224.

Abstract

The reluctance to use estrogen in breast cancer survivors with hot flashes has extended to its use in healthy women since the 2002 publication of the Women's Health Initiative study. This article reviews the clinical development of nonhormonal agents as alternatives to hormonal therapy for the management of hot flashes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adrenergic alpha-Agonists / therapeutic use
  • Amines / therapeutic use
  • Anti-Anxiety Agents / therapeutic use
  • Antidepressive Agents / pharmacology
  • Antidepressive Agents / therapeutic use
  • Antioxidants / therapeutic use
  • Cimicifuga
  • Clonidine / therapeutic use
  • Cyclohexanecarboxylic Acids / therapeutic use
  • Drug Interactions
  • Female
  • Gabapentin
  • Hot Flashes / drug therapy*
  • Humans
  • Isoflavones / therapeutic use
  • Phytotherapy
  • Vitamin E / therapeutic use
  • gamma-Aminobutyric Acid / therapeutic use

Substances

  • Adrenergic alpha-Agonists
  • Amines
  • Anti-Anxiety Agents
  • Antidepressive Agents
  • Antioxidants
  • Cyclohexanecarboxylic Acids
  • Isoflavones
  • Vitamin E
  • gamma-Aminobutyric Acid
  • Gabapentin
  • Clonidine