Abstract
Renal leiomyoma is a rare smooth muscle tumor of the kidney. An association between Epstein-Barr virus and smooth muscle tumors in immunocompromised patients recently has been recognized. We describe a pediatric renal transplant patient who developed an Epstein-Barr virus-associated renal leiomyoma in his transplant kidney 5 years posttransplantation. Possible factors involved in the tumor pathogenesis in our patient are discussed, including immunosuppression, growth hormone therapy, and Epstein-Barr virus induction.
MeSH terms
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Child, Preschool
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Disease Transmission, Infectious
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Epstein-Barr Virus Infections / transmission*
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Female
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Growth Disorders / etiology
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Humans
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Hydronephrosis / complications
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Kidney / abnormalities
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Kidney / chemistry
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Kidney / pathology
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Kidney / virology
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Kidney Failure, Chronic / etiology
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Kidney Failure, Chronic / surgery
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Kidney Function Tests
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Kidney Neoplasms / diagnostic imaging
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Kidney Neoplasms / physiopathology
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Kidney Neoplasms / virology*
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Kidney Transplantation / adverse effects*
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Leiomyoma / diagnostic imaging
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Leiomyoma / physiopathology
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Leiomyoma / virology*
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Male
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Middle Aged
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Nephrectomy
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Nephritis, Interstitial / etiology
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Postoperative Complications / diagnostic imaging
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Postoperative Complications / etiology
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Postoperative Complications / physiopathology
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Postoperative Complications / virology*
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RNA, Viral / analysis
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Radiography
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Recurrence
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Renal Dialysis
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Transplantation, Homologous / adverse effects*
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Ultrasonography
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Urethra / abnormalities
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Urinary Tract Infections / etiology