An arrhythmic-inducing glycoside from Albizzia julibrissin Durazz, IV

Chem Pharm Bull (Tokyo). 1992 Mar;40(3):829-31. doi: 10.1248/cpb.40.829.

Abstract

Three pyridoxine derivatives have been isolated from the fresh stem bark of Albizzia julibrissin DURAZZ.. One of them, named julibrin II, was found to exhibit arrhythmic-inducing action. However, neither the others having the same aglycone nor some glycosides having the same sugar unit showed the action.

MeSH terms

  • Animals
  • Arrhythmias, Cardiac / chemically induced*
  • Drugs, Chinese Herbal / pharmacology*
  • Glucosides / chemistry
  • Glucosides / pharmacology*
  • Magnetic Resonance Spectroscopy
  • Myocardial Contraction / drug effects*
  • Pyridoxine / analogs & derivatives*
  • Pyridoxine / chemistry
  • Pyridoxine / pharmacology
  • Ranidae
  • Spectrometry, Mass, Fast Atom Bombardment

Substances

  • Drugs, Chinese Herbal
  • Glucosides
  • julibrine I
  • julibrine II
  • Pyridoxine