[Stenting plus coiling: dangerous or helpful?]

Rofo. 2005 Sep;177(9):1255-9. doi: 10.1055/s-2005-858503.
[Article in German]

Abstract

Purpose: The purpose of this study was to evaluate the procedural risk of treating acute ruptured aneurysms with a stent-coil combination.

Material and methods: Between August 2001 and January 2004 we treated nine acute subarachnoid hemorrhage (SAH) patients with a combination of stents and platinum coils.

Results: Six aneurysms were 100% eliminated; the residual three aneurysms had a 95% to 99% occlusion. A transient thrombosis in the stent in one patient could be recanalized by intravenous application of ReoPro. In another patient an occlusive vasospasm at the distal end of the stent was successfully treated with intraarterial Nimotop. Neurological complications occurred in none of the patients.

Conclusion: In broad-based aneurysms which cannot be clipped or in which any neurosurgical treatment presents an unacceptably high risk (posterior circulation and paraophthalmic aneurysms), treatment using a combination of stent and platinum coils might be an option even in the acute phase of an SAH. Platelet aggregation can be treated with Aspirin and Plavix after placement of the first coil, vasospasms with intraarterial Nimotop, and acute stent thrombosis with GP IIa/IIIb-antagonists.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Acute Disease
  • Aneurysm, Ruptured / complications
  • Aneurysm, Ruptured / therapy*
  • Angiography, Digital Subtraction
  • Aspirin / administration & dosage
  • Aspirin / therapeutic use
  • Calcium Channel Blockers / administration & dosage
  • Calcium Channel Blockers / therapeutic use
  • Cerebral Angiography*
  • Clopidogrel
  • Embolization, Therapeutic*
  • Follow-Up Studies
  • Humans
  • Intracranial Aneurysm / complications
  • Intracranial Aneurysm / therapy*
  • Nimodipine / administration & dosage
  • Nimodipine / therapeutic use
  • Platelet Aggregation Inhibitors / administration & dosage
  • Platelet Aggregation Inhibitors / therapeutic use
  • Platinum
  • Risk Factors
  • Stents* / adverse effects
  • Subarachnoid Hemorrhage / etiology
  • Ticlopidine / administration & dosage
  • Ticlopidine / analogs & derivatives
  • Ticlopidine / therapeutic use
  • Time Factors
  • Treatment Outcome
  • Vasodilator Agents / administration & dosage
  • Vasodilator Agents / therapeutic use

Substances

  • Calcium Channel Blockers
  • Platelet Aggregation Inhibitors
  • Vasodilator Agents
  • Platinum
  • Nimodipine
  • Clopidogrel
  • Ticlopidine
  • Aspirin