Dendridine A, a bis-indole alkaloid from a marine sponge Dictyodendrilla Species

J Nat Prod. 2005 Aug;68(8):1277-8. doi: 10.1021/np050076e.

Abstract

A unique C2-symmetrical 4,4'-bis(7-hydroxy)indole alkaloid, dendridine A (1), was isolated from an Okinawan marine sponge Dictyodendrilla sp., and the structure was elucidated by spectroscopic data. Dendridine A (1) exhibited antibacterial and antifungal activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Indole Alkaloids / chemistry
  • Indole Alkaloids / isolation & purification*
  • Indole Alkaloids / pharmacology
  • Japan
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Porifera / chemistry*

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Indole Alkaloids
  • dendridine A