Videothoracoscopy is a useful diagnostic tool in patients with suspicion of malignant pleural effusion, because of both: the high accuracy in diagnosis and the possibility of assessing the extent of pleural involvement and producing the pleurodesis. An analysis of characteristics of 110 patients with suspected pleural dissemination is presented, including final diagnosis established with the use of VTS. In patients with confirmed malignant pleural effusion following characteristics were analyzed: the extent of pleural metastatic involvement, type of the primary malignancy, possibility of re-expansion of the lung and patients survival according to the primary tumor and extent of involvement of the pleura.