Abstract
Metastasis from extracranial tumor into an intracranial primary tumor is an uncommon event. A predominant tendency of meningioma to be the host tumor for breast carcinoma has been found. In the current report, three cases of breast carcinoma metastatic to intracranial meningiomas are described. In our cases, metastasis in meningioma was the first clinical manifestation of the occult primitive breast carcinoma. We review widely the literature concerning such rare occurrences and discuss all the postulated pathogenetic mechanisms. There are few cases reported in the literature on resonance magnetic imaging of metastatic carcinoma in meningioma. Two of our patients have been studied by MRI, but we do not find predictive radiological finding of this particular association.
MeSH terms
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Adenocarcinoma / chemistry
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Adenocarcinoma / diagnosis
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Adenocarcinoma / pathology
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Adenocarcinoma / secondary*
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Adult
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Aged
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Breast Neoplasms / chemistry
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Breast Neoplasms / diagnosis
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Breast Neoplasms / pathology*
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Female
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Humans
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Immunohistochemistry
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Keratins / analysis
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Magnetic Resonance Imaging
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Male
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Mammography
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Meningeal Neoplasms / chemistry
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Meningeal Neoplasms / diagnosis
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Meningeal Neoplasms / pathology*
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Meningeal Neoplasms / secondary*
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Meningioma / chemistry
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Meningioma / diagnosis
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Meningioma / pathology*
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Middle Aged
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Neoplasms, Multiple Primary / chemistry
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Neoplasms, Multiple Primary / diagnosis
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Neoplasms, Multiple Primary / pathology*
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Receptors, Estrogen / analysis
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Receptors, Progesterone / analysis
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Vimentin / analysis
Substances
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Receptors, Estrogen
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Receptors, Progesterone
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Vimentin
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Keratins