Abstract
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) is characterised by a rare multisystem disorder of unknown pathogenesis. Although its pathophysiology is not well understood, overexpression of proinflammatory cytokines has been implicated. Gastrointestinal system disorders have not been reported among the components of the syndrome. A case is reported of POEMS syndrome with gastrointestinal involvement shown by gastrointestinal endoscopy.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Cyclophosphamide / therapeutic use
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Doxorubicin / therapeutic use
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Female
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Gastrointestinal Diseases / complications*
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Gastrointestinal Diseases / drug therapy
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Gastrointestinal Diseases / pathology
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Humans
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Intestinal Mucosa / pathology
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POEMS Syndrome / complications*
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POEMS Syndrome / drug therapy
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POEMS Syndrome / pathology
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Prednisone / therapeutic use
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Vincristine / therapeutic use
Substances
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisone