Abstract
We compared PCR with blood cultures in the diagnosis of neonatal staphylococcal sepsis. Significant association was observed between PCR-based and culture-based diagnosis of staphylococcal bacteremia. Positive and negative predictive values for PCR were 100% and 98%, respectively. These data indicate that PCR may serve as a useful adjunct for the rapid diagnosis of staphylococcal sepsis.
Publication types
-
Comparative Study
-
Evaluation Study
MeSH terms
-
Bacteremia / diagnosis*
-
Bacteremia / microbiology
-
Bacteriological Techniques
-
Blood / microbiology
-
Culture Media
-
DNA, Bacterial / analysis
-
Female
-
Humans
-
Infant
-
Infant, Low Birth Weight
-
Infant, Newborn
-
Infant, Premature
-
Infant, Premature, Diseases / diagnosis*
-
Infant, Premature, Diseases / microbiology
-
Intensive Care Units, Neonatal
-
Male
-
Polymerase Chain Reaction / methods*
-
Predictive Value of Tests
-
Sensitivity and Specificity
-
Staphylococcal Infections / diagnosis*
-
Staphylococcal Infections / microbiology
-
Staphylococcus / classification
-
Staphylococcus / genetics
-
Staphylococcus / isolation & purification*
Substances
-
Culture Media
-
DNA, Bacterial