Stroke in two children with Mycoplasma pneumoniae infection. A causal or casual relationship?

Pediatr Infect Dis J. 2005 Sep;24(9):843-5. doi: 10.1097/01.inf.0000177284.88356.56.

Abstract

We report on 2 children who had a stroke biologically related to Mycoplasma pneumoniae infection. Invasion of the central nervous system and an immune mechanism represent 2 pathogenesis pathways. Prompt macrolide therapy does not prevent stroke, but immediate and aggressive immunosuppressive treatment seems to help recovery.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Cerebrospinal Fluid / microbiology
  • Child
  • Child, Preschool
  • Disease Progression
  • Drug Therapy, Combination
  • Electrocardiography
  • Fatal Outcome
  • Female
  • Humans
  • Immunotherapy / methods
  • Male
  • Mycoplasma pneumoniae / isolation & purification*
  • Pneumonia, Mycoplasma / complications*
  • Pneumonia, Mycoplasma / diagnosis*
  • Pneumonia, Mycoplasma / drug therapy
  • Risk Assessment
  • Severity of Illness Index
  • Stroke / diagnosis
  • Stroke / etiology*
  • Stroke / therapy
  • Tomography, X-Ray Computed

Substances

  • Anti-Bacterial Agents